About 14% of patients who recovered from the novel coronavirus and were discharged from hospitals in southern China’s Guangdong province were tested positive again in later check-ups, according to the local health authority. A positive test suggests the recovered patients may still carry the virus, adding complexity to efforts to control the outbreak.
There is no clear conclusion on why it happens and whether such patients could still be infectious, said Song Tie, deputy director of the Guangdong Center of Disease Control And Prevention (Guangdong CDC), at a Tuesday briefing.
According to the preliminary assessment, experts believed the patients are still recovering from lung infections and have yet to be fully healthy, according to Song.
According to the latest treatment guidelines for the Covid-19 issued by the National Health Commission, patients can be considered recovered and released from hospital when their throat or nose swabs show up negative in two consecutive tests, with a CT scan indicating no lung lesions, and when they have no obvious symptoms such as fever.
The guidelines suggest recovered patients should monitor their health and limit outdoor activities for two weeks after leaving the hospital, and check in for retesting in following weeks.
Some patients’ test results returned to positive in the follow-up checks, said Li Yueping, director of the intensive care unit at Guangzhou No.8 People’s Hospital at the briefing.
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The No.8 People’s Hospital has found 13 discharged patients that tested positive again, although none showed renewed symptoms, according to Li. Nucleic acid tests for 104 close contacts of the patients all found negative results, said Li.
Cai Weiping, director of the Infectious Diseases Division of the No.8 People’s Hospital, told Caixin that the positive results in the recovered patients were all found from anal swabs, a method rarely used in other parts of the country. Their results were in the “weak positive” range, said Cai.
The national treatment guideline only requires tests from throat or nose swabs for suspected patients as the virus is believed to spread mainly via respiratory droplets produced when an infected person coughs or sneezes. But research by Guangzhou Medical University found the virus in fecal samples, suggesting a new path of transmission. Some hospitals in Guangdong have since adopted the anal swab in virus tests.
Cai said it is still unclear whether the virus detected in the recovered patients is still active. There is also the possibility of a discrepancy in samples, he said.
Song at Guangdong CDC said the province is preparing to put those recovered patients who re-tested positive under concentrated observation. Health authorities will also step up monitoring of discharged patients and their condition as they recover, said Song.
By the end of Monday, Guangdong reported 1,347 infections and 805 recoveries. The death toll reached seven, official data showed.
Similar cases of recovered patients testing positive have been reported elsewhere in China.
Last week, a patient initially discharged after recovering in southwestern Sichuan province’s Chengdu city was readmitted after testing positive again in later check-ups.
Health authorities in the southern island province of Hainan also confirmed that some recovered patients had tested positive again. The authorities required discharged patients to stay home under quarantine for 14 days, and allowed them to be released after both throat and anal swab tests showed negative.
Contact reporter Han Wei (firstname.lastname@example.org)
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